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Research : CNS Funded Projects
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"During the 1990s, researchers learned about the workings of the brain. With our support, in the decade to come, scientists will totally transform medicine by learning how the brain can be repaired and regenerated."
Fia Richmond, Founder and President
Children's Neurobiological Solutions Foundation
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2005 - 2008
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| Title: |
Using Stem Cells to Restore
Function to Brain Cells
Corrupted by Sandhoff Disease
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| Principal Investigators: |
Evan Snyder MD, PhD,
Burnham Institute, La Jolla California
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| Description: |
Evan Snyder, MD, PhD, Professor and Director of the Stem Cells and Regeneration Program at the Burnham Institute in California, will perform preclinical research to investigate the use of human neural stem cells (hNSCs) as a therapy for Sandhoff Disease (SD), a lysosomal storage disorder that is fatal within the first few years of life. . . .
Click here to read the full description and progress report
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| Title: |
Perinatal Implantation of
Human Glial Progenitor
Cells as a Treatment Strategy
for the Childhood Myelin Disorders
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| Principal Investigators: |
Steve Goldman, MD, PhD, Professor of Neurology and Neurosurgery, University of Rochester Medical Center
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| Description: |
The objective of this project is to analyze specific brain cells called “oligodendrocyte progenitor cells”, or OPCs, for their potential to treat a class of diseases called the childhood myelin disorders. These are congenital neurological diseases characterized by a loss of myelin, a critical component of the brain and spinal cord, the loss of which severely retards brain development in children. . . .
Click here to read the full description and progress report
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2001-2004
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| CNS Project 1: |
Degenerative Diseases as a Diesase of Stem Cells
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| Co-Principal Investigators: |
Evan Snyder, Burnham Institute, La Jolla California
Harley Kornblum, University of California, Los Angeles
Mahendra Rao, National Institutes of Aging
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| Description: |
This project asks if some degenerative diseases of the nervous system occur because of defects in the development from stem cells. . .
Click here to read the full description and progress report
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| CNS Project 2: |
Cell Therapy in the Treatment of Diffuse Disease of the Developing Brain and Spinal Cord
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| Co-Principal Investigators: |
Mark D. Noble, University of Rochester
Jeffrey D. Macklis, Harvard Medical School
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| Description: |
This research team is particularly interested in addressing the biology of the neurological disorders of childhood that have no specific location or specific structural damage, but are "global," meaning that they affect and are distributed over the entire
brain. . . .
Click here to read the full description and progress report
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| CNS Project 3: |
Development of a Means to "Label"
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| Co-Principal Investigators: |
Dr. Clive Svendsen, University Wisconsin-Madison
Dr. Mahendra Rao, National Institutes of Aging
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| Description: |
These scientists have been making steady progress in identifying markers to locate transplanted stem cells and upon developing a new type of rat for research, one that more closely mimics human diseases. . . .
Click here to read the full description and progress report
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CNS Research
Learn about the new science of Regenerative Medicine
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